para-TINA for triplex forming oligonucleotides

Papers on the use of TINA in triplex-binding oligonucleotides

LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures

Pabon-Martinez YV, Xu Y, Villa A, Lundin KE, Geny S, Nguyen CH, Pedersen EB, Jørgensen PT, Wengel J, Nilsson L, Smith CIE, Zain R.
Sci Rep. 2017 Sep.

PNA-COMBO-FISH: From combinatorial probe design in silico to vitality compatible, specific labelling of gene targets in cell nuclei

Müller P, Rößler J, Schwarz-Finsterle J, Schmitt E, Hausmann M.
Exp Cell Res. 2016 July.

Interdependence of pyrene interactions and tetramolecular G4-DNA assembly

Doluca O, Withers JM, Loo TS, Edwards PJ, González C, Filichev VV.
Org Biomol Chem. 2015 March.

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

Cogoi S, Zorzet S, Rapozzi V, Géci I, Pedersen EB, Xodo LE.
Nucleic Acids Res. 2013 April.

Improved inhibition of telomerase by short twisted intercalating nucleic acids under molecular crowding conditions

Agarwal T, Pradhan D, Géci I, El-Madani AM, Petersen M, Pedersen EB, Maiti S.
Nucleic Acid Ther. 2012 Dec.

Triplex-forming twisted intercalating nucleic acids (TINAs): design rules, stabilization of antiparallel DNA triplexes and inhibition of G-quartet-dependent self-association

Doluca O, Boutorine AS, Filichev VV.
Chembiochem. 2011 Oct.

Increasing the analytical sensitivity by oligonucleotides modified with para- and ortho-twisted intercalating nucleic acids--TINA

Schneider UV, Géci I, Jøhnk N, Mikkelsen ND, Pedersen EB, Lisby G.
PLoS One. 2011.

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

Pedersen EB, Nielsen JT, Nielsen C, Filichev VV.
Nucleic Acids Res. 2011 March.

Optimal design of parallel triplex forming oligonucleotides containing Twisted Intercalating Nucleic Acids--TINA

Schneider UV, Mikkelsen ND, Jøhnk N, Okkels LM, Westh H, Lisby G.
Nucleic Acids Res. 2010 July.

A novel FRET pair for detection of parallel DNA triplexes by the LightCycler
Uffe V Schneider, Jette K Severinsen, Imrich Géci, Limei M Okkels, Nina Jøhnk, Nikolaj D Mikkelsen, Teena Klinge, Erik B Pedersen, Henrik Westh and Gorm Lisby
BMC Biotechnol. 2010 Jan.

Optimization of the sequence of twisted intercalating nucleic acids (TINA) forming triple helix with the polypurine tract of the proviral HIV DNA

Boutorine AS, Doluca O, Filichev VV.
Nucleic Acids Symp Ser (Oxf). 2009.

High physiological thermal triplex stability optimization of twisted intercalating nucleic acids (TINA)

Bomholt N, Osman AM, Pedersen EB.
Org Biomol Chem. 2008 Oct.

1-, 2-, and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids: structure, thermal stability, and fluorescence relationship

Filichev VV, Astakhova IV, Malakhov AD, Korshun VA, Pedersen EB.
Chemistry. 2008.

DNA glue: 1-, 2- and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids (TINAs), DNA duplexes/triplexes and interstrand excimer formation

Filichev VV, Astakhova IV, Malakhov AD, Korshun VA, Pedersen EB.
Nucleic Acids Symp Ser (Oxf). 2008.

Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

Paramasivam M, Cogoi S, Filichev VV, Bomholt N, Pedersen EB, Xodo LE.
Nucleic Acids Res. 2008 June.

Stabilization of parallel triplexes by twisted intercalating nucleic acids (TINAs) incorporating 1,2,3-triazole units and prepared by microwave-accelerated click chemistry

Géci I, Filichev VV, Pedersen EB.
Chemistry. 2007.